Hardness assurance implications of bimodal total dose response in a bipolar linear voltage comparator

Chemical hardness, linear response, and pseudopotential transferability.

We propose a systematic method of analyzing pseudopotential transferability based on linear-response properties of the free atom, including self-consistent chemical hardness and polarizability. Our calculation of hardness extends the approach of Teter1 not only by including self-consistency, but also by generalizing to non-diagonal hardness matrices, thereby allowing us to test for transferabil...

Comparison of SETs in Bipolar Linear Circuits Generated with an Ion Microbeam, Laser Light and Circuit Simulation

-Generally good agreement was obtained between the single-event output voltage transient waveforms obtained by exposing individual circuit elements of a bipolar comparator and operational amplifier to an ion microbeam, a pulsed laser beam, and circuit simulations using SPICE. The agreement was achieved by adjusting the amounts of charge deposited by the laser or injected in the SPICE simulation...

Some implications of linear-quadratic-linear radiation dose-response with regard to hypofractionation.

Recent technological advances enable radiation therapy to be delivered in a highly conformal manner to targets located almost anywhere in the body. This capability has renewed the clinical interest in hypofractionation wherein the tumor is delivered a few fractions of very large dose per fraction. Extrapolating clinical experience from conventional regimens to fractions of high dose is importan...

Testing and Hardness Assurance Guidelines for Single Event Transients (SETs) in Linear Devices

Quality assurance prusedore in high dose rate bracythrapy

Introduction: Quality assurance is essential for obtaining the best achievable tumor control, avoiding unnecessary side effects, accuracy and safety during performing High Dose Rate (HDR) Brachytherapy (BT). Quality assurance is extremely important because HDR BT procedures are performed quickly, with high doses given in a short time period, with little opportunity for correcti...